The post holder will assist in providing statistical advice and support in the design, conduct and analysis of clinical studies and allied research within the Birmingham Clinical Trials Unit (BCTU).
This is a training post, so the individual suitable for this post would be someone either currently undertaking or a recent graduate from a post-graduate degree course in statistics.
Scope of the Role
The post holder will assist in providing statistical advice and support to BCTU's clinical trial, diagnostic and test evaluation research programme that addresses a wide and interesting range of medical problems of practical relevance to patients, carers and health care providers. The post holder will work alongside a number of statisticians supporting studies within BCTU, under the direction of a senior statistician. The Unit is currently running studies in coloproctology, neurosciences, obstetrics and gynaecology, primary care, renal disease, surgery, burns, trauma and critical care.
Main duties and Responsibilities
- Contribute to the statistical design of clinical trials, diagnostic and test evaluation studies, under the direction of a senior member of the Statistics Team.
- Assist senior members of the Statistics Team with the writing of study protocols and the development of data collections forms.
- Assist senior members of the Statistics Team in the development and testing of data management systems.
- Contribute to statistical analysis plans under the direction of a senior member of the Statistics Team.
- Undertake statistical analysis to assist Trial Co-ordinators in the running of studies, and carry out data checking routines to report on the data quality of on-going studies.
- Undertake appropriate statistical analysis of study data and provide results to include in reports for Data Monitoring and Steering Committees and for inclusion in presentations and publications, under the direction of a senior member of the Statistics Team.
- Contribute to the Unit’s support and advice service, under the direction of a senior member of the Statistics team.
- Assist senior members of the Statistics Team with teaching and research training activities.
- Contribute to statistical methodological research relevant to the studies being undertaken within BCTU.
- Support the delivery of clinical research in accordance with Good Clinical Practice (GCP), the Declaration of Helsinki, applicable legislation (including, but not limited to, the Medicines for Human Use Clinical Trials Regulations, Data Protection Act, Human
- Tissue Act), the Research Governance Framework for Health and Social Care, Caldicott principals, and applicable NHS Trust and University policies and procedures, (including, but not limited to the University’s Data Protection Policy, Information Security Policy and Code of Practice for Research) in order to protect the research subject and the quality of each study.
- MSc or PhD in Statistics.
- Students currently studying for an MSc or PhD in Statistics who are due to complete these degrees in the next 6 months are also eligible for apply.
- Knowledge of medical statistics, clinical trials, diagnostic and test evaluation studies.
- Knowledge of statistical techniques e.g. linear, logistic and Cox regression, analysis of variance, repeated measures, survival analysis.
- Knowledge of statistical analysis packages, preferably SAS and/or STATA.
- Knowledge of computer-based database management and data extraction/ reporting techniques (preferably Access/SQL).
- Knowledge of the protected characteristics of the Equality Act 2010, and how to actively ensure in day to day activity in own area that those with protected characteristics are treated equally and fairly.
- Ability to work well as part of a team.
- Good inter-personal, verbal and written communication skills.
- Meticulous attention to detail and high levels of accuracy.
- Aptitude for analysis which is real life and problem driven.
- Interest in the application of statistical techniques for medical problems.
- Willingness to learn new techniques.
- Ability to impart statistical concepts to non-statisticians.
This training post provides an excellent opportunity for someone either currently undertaking or a recent graduate from a post-graduate degree course in statistics to gain the necessary experience to develop into a medical statistician within a leading academic trials unit. The post holder will work alongside senior members of the Statistics team supporting studies within BCTU, and would receive sufficient mentoring and training such that they could work more independently with less supervision after at least 2 years into the appointment.
Statisticians play a central role in the Unit, actively liaising with clinical investigators, contributing to the design and conduct of clinical trials, being responsible for interim and final analysis of clinical trial data and having a key role in the presentation and publication of results. As academic members of the University, statisticians contribute to teaching at undergraduate and postgraduate level.
Statisticians are encouraged to take an interest in the medical areas, and understand the clinical issues and problems relating to the disease areas in which they work. This enables them to contribute to disease-specific research at a national and international level.